NuGel-HemogloBind™
Hemoglobin Removal with NuGel™ Dry-Bead Format
• Has a high degree of specificity for hemoglobin binding up to 10 mg/ml
• Species agnostic; including human, mouse, rat, sheep, bovine, goat, etc
• Removes hemoglobin from clarified organ/tissue lysates.
• Hemoglobin removal from red blood cell lysate for proteomics and biomarker drug discovery
• The flow through fractions (hemoglobin depleted) retain their enzymatic and biological activity
• Compatible with LC-MS, activity-based profiling and proteomic investigations
• Validated in the automation compatible high-throughput DPX Technologies XTR tip format
NuGel™ Hemoglobind™ is a modified version of suspension HemogloBind™, engineered for increased stability and improved installation for high-throughput formats. It is based on NuGel™ silica (50 microns in size, 1000Å) covalently bound to elastomeric polyelectrolytes. Comparable to selection properties of suspension HemogloBind™, at recommended quantities, >95% of hemoglobin can be removed with very high selectivity.