Antiepileptics in Serum / Plasma with UHPLC 质谱方案

Antiepileptics with UHPLC
This ClinRep® UHPLC Complete Kit shows an identical analyte spectrum as the ClinRep® HPLC Complete Kit with order no. 14000. Thus, the following 16 substances can be quantified simultaneously: carbamazepine, eslicarbazepine, ethosuximide, felbamate, lacosamide, lamotrigine, oxcarbazepine, phenobarbital, phenytoin, primidone, rufinamide, sulthiame and zonisamide as well as the pharmacologically active metabolites N-desmethylmethsuximide, 10-hydroxycarbamazepine and carbamazepine epoxide. The chromatographic separation is performed with an injection interval of 5 min only.

This ClinRep® UHPLC Complete Kit shows an identical analyte spectrum as the ClinRep® HPLC Complete Kit with order no. 14000. Thus, the following 16 substances can be quantified simultaneously: carbamazepine, eslicarbazepine, ethosuximide, felbamate, lacosamide, lamotrigine, oxcarbazepine, phenobarbital, phenytoin, primidone, rufinamide, sulthiame and zonisamide as well as the pharmacologically active metabolites N-desmethylmethsuximide, 10-hydroxy-carbamazepine and carbamazepine epoxide. The chromatographic separation is performed with an injection interval of 5 min only.
Sample Preparation

Chromatography

Ordering Information

Order No.	Description	Quantity
BYRI-14100	ClinRep® Complete Kit for Antiepileptics	1 pce.
	in Serum / Plasma by UHPLC
	for 100 assays
	Contents:
	Mobile Phase A	1 x 14108
	Mobile Phase B	1 x 14109
	Standard Solution Antiepileptics 3	1 x 14011
	Standard Solution Antiepileptics 4	1 x 14111
	Precipitant P with Internal Standard	1 x 14012
	Serum Calibrator Antiepileptics 3, lyophil.	1 x 14013
	Sample Preparation Vials	1 x 14020
	Diluting Solution D	1 x 14021
	Separately available components:
BYRI-14108	Mobile Phase A	400 ml
BYRI-14109	Mobile Phase B	200 ml
BYRI-14011	Standard Solution Antiepileptics 3	3 ml
BYRI-14111	Standard Solution Antiepileptics 4	3 ml
BYRI-14012	Precipitant P with Internal Standard	20 ml
BYRI-14013	Serum Calibrator Antiepileptics 3, lyophil.	3 ml
BYRI-14113	Serum Calibrator Antiepileptics 4, lyophil.	3 ml
BYRI-14020	Sample Preparation Vials	100 pcs.
BYRI-14021	Diluting Solution D	25 ml
	Start Accessory:
BYRI-14130	Analytical Column with test chromatogram	1 pce.
	ClinChek® Controls:
BYRI-14082	Serum Control Antiepileptics 3, lyophil.Level I, II	2 x 5 x 3 ml
BYRI-14182	Serum Control Antiepileptics 4, lyophil.Level I, II	2 x 5 x 3 ml

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